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Saturday, September 27, 2025

Atypical myopathy in horses: all you could know


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    This text has been edited and accredited by Karen Coumbe MRCVS, H&H’s veterinary advisor since 1991.
  • Atypical myopathy in horses (also referred to as seasonal pasture myopathy, sycamore myopathy or sycamore poisoning) is an typically deadly sickness, often present in grazing equines — largely within the autumn and spring.

    The British Equine Veterinary Affiliation (BEVA) launched a press release in mid October 2024 reminding homeowners of the risks related to horses grazing round sycamore timber as they shed their seeds.



    “With leaves nonetheless on timber now could be the time to establish sycamores within the neighborhood of your horse’s fields and predict the long run danger,” stated Lucy Grieve, veterinary tasks officer at BEVA “As soon as the leaves begin to flip after which drop it is going to be way more tough to identify sycamores.”

    This severe menace to horses’ well being weakens the muscle tissues of the horse’s physique, together with the center, and may current with sudden stiffness, muscle tremors, collapse and colic-like indicators, accompanied by a low temperature. Usually darkish urine is seen as a result of the broken muscle cells launch the pigment myoglobin, which may injury the kidneys.

    Atypical myopathy has a fatality price of round 70% so ought to all the time be thought-about a veterinary emergency whether it is suspected.

    Atypical myopathy will not be infectious and may have an effect on horses of all ages and kinds, though younger horses could also be extra susceptible. Some horses seem like extra inclined than others, which can be resulting from genetic variations.

    Atypical myopathy: Causes | Dangers | Indicators | Analysis | Remedy | Prognosis | Prevention

    What causes atypical myopathy in horses?

    Research have established that atypical myopathy is brought on by ingestion of the hypoglycin A toxin from the seeds, seedlings and presumably flowers of sure timber of the genus Acer. The most typical of this sort within the UK is the sycamore tree, however completely different timber comprise variable quantities of the toxin. It is very important word that the toxin will not be current in each seed, seedling or tree.

    The Royal Veterinary School supplies a hypoglcyin A check which can be utilized on each plant samples and equine serum to establish the extent of the toxin.

    Hypoglycin A prevents power being produced inside the muscle cells.

    A lot analysis has been accomplished by the College of Liege and concerned horses from Belgium, Germany and the Netherlands. Excessive concentrations of hypoglycin A had been present in all of the sick horses. Botanists visited the pastures that had been grazed and the sycamore was discovered to be close by in each case.

    In the USA analysis has linked seasonal pasture myopathy (the US equal) to toxins from the field elder tree. Each timber produce seeds containing the agent hypoglycin A.

    Sycamore seeds hanging in clumps on a tree

    Sycamore seeds have a downward V form with “wings” to assist them journey on the wind, whereas the leaves of the timber have 5 factors.

    The “helicopter” wing-shaped seeds are considered the first supply of the toxin, however sycamore seedlings have additionally been discovered to comprise the toxin, being a specific concern within the spring. It is suggested that seedlings are mowed and the cuttings collected and faraway from the pasture afterwards because the poisonous hypoglcyin A stays within the plant materials after it has been minimize.

    Acer pseudoplatanus, a sycamore seedling, which is linked to the often fatal condition of atypical myopathy in horses

    Sycamore seedlings are additionally a trigger for concern and needs to be faraway from pastures the place horses graze.

    When are horses most in danger?

    Outbreaks of the deadly situation are usually seasonal, with instances sometimes occurring within the autumn and spring. Victims are often saved in sparse pastures, the place seeds or seedlings are on the bottom and are eaten when there’s not a lot different grazing obtainable. Windy autumn climate is especially dangerous as it will possibly deposit massive numbers of sycamore seeds on to grazing land, that are then eaten. 

    What are the indicators of atypical myopathy in horses?

    The onset of the illness will be extraordinarily speedy, with some horses being discovered collapsed or lifeless of their fields. Indicators embrace:

    • Stiffness
    • Weak spot
    • Reluctance to maneuver
    • Lethargy
    • Muscle tremors
    • Muscle ache
    • Sweating
    • Issue respiratory
    • Shivering
    • Darkish purple or brown urine
    • Quick, irregular coronary heart beat
    • Colic indicators
    • Unable to face
    • Sudden collapse and loss of life

    How is it recognized?

    Your vets will be capable of make a possible prognosis primarily based on the medical indicators in addition to the horse’s setting, together with lab assessments to substantiate the degrees of toxicity.

    What therapy is on the market?

    Horses recognized early will want therapy with intravenous fluids, ache reduction and intensive care at an equine hospital, however as soon as the indicators are current it’s already severe. Affected animals typically deteriorate for the primary 24 to 48 hours so needs to be moved to an equine hospital as quickly as attainable after the prognosis is made because the interval the horse is ready to stay standing whereas in transit goes to be restricted.

    There’s a compromise in that the horses don’t wish to be moved far, nonetheless efficient intensive care will not be actually attainable within the area, the place they could be ingesting extra toxin.

    Supportive remedy together with nutritional vitamins, minerals and antioxidants could also be useful.

    A 2018 examine confirmed that activated charcoal could bind the toxin, so your vet could contemplate abdomen tubing with this following removing of any instances from pasture.

    Atypical myopathy in horses: what’s the prognosis?

    With some 70% of instances proving deadly, the prognosis for horses with atypical myopathy is cautious at greatest. Nevertheless, if a horse can survive the primary few days of therapy, they’ll go on to make a full restoration over a interval of some months with no long-term results of the illness.

    How can homeowners cut back the chance?

    • Establish timber each round grazed fields in addition to these in shut proximity
    • Fence off areas the place sycamore seeds and/or leaves have fallen
    • Repeatedly examine fields to make sure seeds haven’t blown in from close by sycamore timber
    • Mow areas the place seedlings are rising and acquire the cuttings
    • Provide additional forage (hay or haylage), particularly the place pasture is poor
    • Cut back inventory density, so there’s sufficient good grazing for each horse
    • Prove horses for brief intervals (ideally lower than 6hrs.)
    • Choose up and take away sycamore seeds, if attainable
    • Take a look at for the presence of hypoglcyin A in your pastures
    • Monitor horses fastidiously and if involved, contact your vet instantly

    If a case happens and your horse is in the identical area, ask your vet for recommendation and contemplate shifting your horse.

    Additional studying:
    Royal Veterinary School’s atypical myopathy reality sheet for horse homeowners [PDF] – 2022

    Solutions to the Often Requested Questions Relating to Horse Feeding and Administration Practices to Cut back the Danger of Atypical Myopathy – February 2020

    Equine atypical myopathy within the UK: Epidemiological traits of instances reported from 2011 to 2015 and components related to survivalApril 2017

    The Story of Equine Atypical Myopathy: A Overview from the Starting to a Doable Finish – November 2012

    You may additionally be involved in:

    As autumn rolls on, confirmed instances of acorn poisoning improve. Sarah Smith MRCVS outlines the risks for horses grazing in

    Whereas many vegetation will be toxic if eaten to extra, there are some toxic vegetation that horses ought to keep away from at


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